Sleep study

Hierarchical and Mixed Effects Models in R

Richard Erickson

Data Scientist

Overview of sleep study

• Two soporific drugs
• 10 patients
• Classic dataset used by "Student"

Research question

• ANOVA type analysis:
  • $H_0$: Drug type term does not explain a significant amount of variability
  • $H_a$: Drug type term explains a significant amount of variability
• Regression coefficient approach
  • $H_0$: Drug type term is zero
  • $H_a$: Drug type term is not zero

Modeling approach

• Visualize data
• Build simple model
• Build model of interest
• Extract information of interest
• Visualize results

Let's practice!

Hierarchical and Mixed Effects Models in R